The first time Jay Keasling remembers hearing the word “artemisinin,” about a decade ago, he had no idea what it meant.

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At a hearing on Capitol Hill in May, James Moroney, the publisher of the Dallas Morning News, told Congress about negotiations he’d just had with the online retailer Amazon. The idea was to license his newspaper’s content to the Kindle, Amazon’s new electronic reader. “They want seventy per cent of the subscription revenue,” Moroney testified.

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The newspaper is dead. You can read all about it online, blog by blog, where the digital gloom over the death of an industry often veils, if thinly, a pallid glee. The Newspaper Death Watch, a Web site, even has a column titled “R.I.P.” Or, hold on, maybe the newspaper isn’t quite dead yet. At its funeral, wild-eyed mourners spy signs of life. The newspaper stirs!

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When the Tribune Company announced that it was filing for bankruptcy, last Monday, Sam Zell, the man who bought the company a year ago, for $8.2 billion, said that its problems were the result of a “perfect storm.” You take readers and advertisers who were already migrating away from print, and add a steep recession, and you’ve got serious trouble. What Zell failed to mention was that his acquisition of the company had buried it beneath such a heavy pile of debt that any storm at all would likely have sunk it.

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Last December, a friend and I went to a release party for Mary J. Blige’s “Growing Pains” album. Near huge screens showing Blige videos, a d.j. was playing records on two turntables. The d.j.’s eyes, however, were trained on an Apple MacBook on a shelf above them.

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It wasn’t so long ago ago that Tina Brown and Bonnie Fuller were busy transforming entire magazine genres. They lived on opposite ends of the taste spectrum–Brown edited Vanity Fair and the New Yorker, Fuller revamped Glamour, then re-invented the celebrity gossip concept at Us Weekly and later the Star–but the two had a similar [...]

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This spring marked the 40th anniversary of HAL, the conversational computer that was brought to life in the 1968 film “2001: A Space Odyssey.” Forty years after “2001,” how close are we to talking to a computer? Current applications of speech technology are a far cry from HAL.

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In 1999, when Nathan Myhrvold left Microsoft and struck out on his own, he set himself an unusual goal. He wanted to see whether the kind of insight that leads to invention could be engineered. He formed a company called Intellectual Ventures. He raised hundreds of millions of dollars. He hired the smartest people he knew. … Myhrvold wanted to make insights–to come up with ideas, patent them, and then license them to interested companies. … One rainy day last November, Myhrvold held an “invention session,” as he calls such meetings, on the technology of self-assembly. What if it was possible to break a complex piece of machinery into a thousand pieces and then, at some predetermined moment, have the machine put itself back together again? That had to be useful. But for what?

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Three centuries after the appearance of Franklin’s Courant, it no longer requires a dystopic imagination to wonder who will have the dubious distinction of publishing America’s last genuine newspaper. Few believe that newspapers in their current printed form will survive. Newspaper companies are losing advertisers, readers, market value, and, in some cases, their sense of mission at a pace that would have been barely imaginable just four years ago.

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In June, 2006, Sergey Brin, one of the co-founders of Google, went to Washington, D.C., hoping to create a little good will. Google was something of a Washington oddity then. Although it was a multibillion-dollar company, with enormous power, it had no political-action committee, and its Washington office had opened, in 2005, with a staff of one, in suburban Maryland. The visit, which was reported in the Washington Post, was hurried, and, in what was regarded by some as a snub, Brin failed to see some key people, including Sen. Ted Stevens, of Alaska, who was then the chairman of the Commerce Committee and someone whose idea of the Internet appeared to belong to the analog era. (He once said that a staff member had sent him “an Internet.”)

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